Service
CELLiST Solution Center (CSC) is a fully-equipped research facility located in the Incheon Free Economic Zone, a rapidly developing biotech cluster south of Seoul. Our main role is to support our growing client-base of biopharma companies who use our specialized, customized products, as well as conducting basic R&D for media optimization.
CSC lab employs workflows that allow rapid cell-culture media development, by using hi-tech instrumentation such as robotic systems for
powder formulation and automated micro-bioreactor systems. Analysis of culture data is done using cutting-edge multi-omics approach,
with big data analysis and AI algorithms.
What makes us unique is not only the cutting-edge equipment and the high-quality ingredients that we are using, but also the flexible and
adaptive nature of our operation and our ability to rapidly troubleshoot our customers’ problems and assist them in developing cell-culture
media that is tailored to their precise needs, in the minimum amount of time.
with your cell line by using various media library
Customer Support, Consultation & Remote Services
Cell Adaptation & Media Screening
Scale-up Support
Protein Quality Analysis
| Stage | R&D | Clinical | NDA | Marketed |
|---|---|---|---|---|
| Pipelines | 22 | 21 | 1 | 4 |
Rapid analysis of a newly established CHO cell line was followed with intensive media development process, leading to significantly improved productivity in a short period of time.
Our unique capabilities allow for strong and flexible support to the customer:
Development can be quickly initiated with starting medium optimal for the customer's cell line. Candidate redia calbe rapidly evaluated by an array of industry-leading high throughput systems supported by experienced researchers, Complete, high-throughput analysis of spent media, including amino acids, vitamins, minerals and other components, allows for a customized and efficient optimization. DoE and statistical analysis, combined with our long experience in media formulation, leads to rapid design of optimal composition. Keeping in mind customer goals and deadlines. our professional development team supports the customer throughout the process up to commercialization stage.
Efficient media development and optimization cycles throughout the collaboration with Chugai led to drastic increase in productivity, reaching high protein titer of 12 g/L. In the development process, our proprietary L-Cysteine technology, allowing high concentration and liquid stability, contributed to the largel improvement in titer. In addition, media performance was further enhanced based on in-house knowledge* and additional spent media analysis, optimizing concentrations of potassium and phosphate, among other components.
Precipitation Inhibition
Our proprietary composition stabilized liquid media enhancing L-Cysteine.
Titer Improvement
L-Oysteine high-concentration with liquid-stability increased liter.
