Ajinomoto Genexine cell culture medium CELLiST “Amino acid technology …

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작성자ajinomo 조회 319 작성일 22-06-20 17:29

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Increasing need for amino acid technology required for biopharmaceutical development CELLiST, meets cell growth speed and protein production capacity with high-quality amino acids

In the biopharmaceutical industry, there is a saying that ‘the manufacturing process is the product.’ The manufacturing process is a major factor that determines the success or failure of the efficacy and quality of biopharmaceuticals. In particular, it is no exaggeration to say that cell culture media is the core of the manufacturing process. 

Among them, cell culture media is an essential item that must be used in the process of manufacturing biopharmaceuticals. In other words, selecting an appropriate cell culture medium determines the quality and competitiveness of biopharmaceuticals. However, most domestic bio companies rely on imports for most of their cell culture media.

As the need for amino acid technology for biopharmaceutical development is growing, Ajinomoto Genexine, a company specializing in animal cell culture media, announced that it is contributing to the development of the domestic biopharmaceutical industry through local production of biopharmaceutical raw materials and development technology.

Cell culture media is used to proliferate animal cells and cell therapy products for biopharmaceutical production or to proliferate their functions to produce and maintain biopharmaceuticals. It is composed of nutrients such as amino acids, vitamins, trace metals, and growth factors. It is a chemical composition product. Among these, amino acids are the main raw materials that have a significant impact on cell growth and production, and are composed of growth factors, vitamins, inorganic salts, etc.

Ajinomoto Genexine supplies high-quality cell culture media through its cell culture media product brand CELLiST. High-quality amino acids developed based on Ajinomoto's amino acid research capabilities and technology help meet both cell growth speed and protein production capacity. Additionally, most CHO cell lines can be expected to be utilized, including CHO-K1, CHO-S, CHO-DG44, and CHO-DXB11.

In addition, CELLiST has added differentiation by operating a Switch Program. By providing a service to change the cell culture medium suitable for the various needs of the customer, the customer can become competitive in the industry by improving productivity, improving antibody quality, and reducing production costs. Using CELLiST's switch program, you can change your cell culture medium in as little as 3 to 6 months.

An official from Ajinomoto Genexine said, “We have established production facilities and a management system that complies with pharmaceutical manufacturing and quality management standards (cGMP) to produce a wide range of media, from amino acid mixtures to cell culture media for the production of customized biopharmaceuticals.” He added, “DoE and Digital “By applying cutting-edge systems such as Twin technology, we will shorten the biopharmaceutical manufacturing process period and introduce high-quality products while maintaining price competitiveness.”

Meanwhile, Ajinomoto Genexine CELLiST can provide technical services necessary for changing cell culture media by utilizing the latest cell culture equipment and analysis equipment owned by its own research institute. In addition, CSC (CELLiST Solution Center)'s various equipment (ambr15Ambr15®, Junior, Cedex Bio HT, etc.) and organs are used to fine tune customized optimized research cell culture medium, ambr culture medium screening and supernatant, analysis, as well as biopharmaceutical approval. We provide support with documents necessary for the process.

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